macrophage


macrophage
Relatively long-lived phagocytic cell of mammalian tissues, derived from blood monocyte. Macrophages from different sites have distinctly different properties. Main types are peritoneal and alveolar macrophages, tissue macrophages (histiocytes), Kuppfer cells of the liver, and osteoclasts. In response to foreign materials may become stimulated or activated. Macrophages play an important role in killing of some bacteria, protozoa, and tumour cells, release substances that stimulate other cells of the immune system, and are involved in antigen presentation. May further differentiate within chronic inflammatory lesions to epithelioid cells or may fuse to form foreign body giant cells or Langhans\' giant cells.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Macrophage — A macrophage of a mouse stretching its arms (pseudopodia) to engulf two particles, possibly pathogens. Trypan Blue Exclusion. Latin macrophagocytus …   Wikipedia

  • macrophage — [ makrɔfaʒ ] n. m. et adj. • 1887; de macro et phage ♦ Histol. Grosse cellule dérivant du monocyte du sang, douée du pouvoir d englober et de détruire par phagocytose des corps étrangers volumineux. ⇒ histiocyte. ● macrophage adjectif et nom… …   Encyclopédie Universelle

  • macrophage — mac ro*phage, n. A large phagocyte. [WordNet 1.5] …   The Collaborative International Dictionary of English

  • macrophage — (n.) 1890, from Mod.L. macrophagus, from MACRO (Cf. macro ) + Gk. phagein to devour (see PHAGOUS (Cf. phagous)) …   Etymology dictionary

  • macrophage — [mak′rō fāj΄] n. [ MACRO + PHAGE] any of various large, phagocytic cells in connective tissue, lymphatic tissue, bone marrow, etc. of vertebrates macrophagic [mak΄rōfaj′ik] adj …   English World dictionary

  • Macrophage — Un macrophage de souris avec deux grands prolongements cytoplasmiques Les macrophages (du grec : « gros mangeur », makros = grand, phagein = manger) sont des cellules infiltrant les tissus, découvertes par Elie Metchnikoff en 1883 …   Wikipédia en Français

  • Macrophage — Makrophagen gehören zu den Fresszellen (Phagozyten) und sind als Leukozyten (weiße Blutkörperchen) Zellen des Immunsystems. Sie dienen der Beseitigung von Mikroorganismen durch Phagozytose und stellen stammesgeschichtlich (phylogenetisch) die… …   Deutsch Wikipedia

  • macrophage —    This is a mature form of what is released from the marrow as a monocyte. A macrophage lives long, can digest much detritus, and is able to wear particles of odd food on its outer membrane. This allows T cell and B cell lymphocytes to taste the …   Herbal-medical glossary

  • macrophage — makrofagai statusas T sritis ekologija ir aplinkotyra apibrėžtis Žmogaus ir gyvūnų jungiamojo audinio ląstelės, gebančios pagriebti ir suvirškinti į organizmą patekusius svetimkūnius (pvz., mikroorganizmus, organizmo yrančių audinių daleles).… …   Ekologijos terminų aiškinamasis žodynas

  • macrophage — noun Etymology: International Scientific Vocabulary Date: 1890 a phagocytic tissue cell of the immune system that may be fixed or freely motile, is derived from a monocyte, functions in the destruction of foreign antigens (as bacteria and… …   New Collegiate Dictionary

  • macrophage — n. [Gr. makros, large; phagein, to eat] A large phagocytic cell of the body …   Dictionary of invertebrate zoology


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