low density lipoprotein receptor


low density lipoprotein receptor
(= LDL-receptor)
A cell-surface protein that mediates the endocytosis of LDL by cells. Genetic defects in LDL-receptors lead to abnormal serum levels of LDL and hypercholesterolaemia.

Dictionary of molecular biology. 2004.

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  • low-density lipoprotein — low den·si·ty lipoprotein lō den(t) sət ē n LDL * * * (LDL) see lipoprotein * * * (LDL) a class of lipoproteins responsible for transport of cholesterol to extrahepatic tissues. It is formed in the circulation when very low density lipoproteins… …   Medical dictionary

  • Very low-density lipoprotein — (VLDL) is a type of lipoprotein made by the liver. VLDL is one of the five major groups of lipoproteins (chylomicrons, VLDL, IDL, LDL, HDL) which enable fats and cholesterol to move within the water based solution of the blood stream. It is… …   Wikipedia


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