LFA-3
(= lymphocyte function-related antigen-3)
Ligand for the CD2 adhesion receptor that is expressed on cytolytic T-cells. LFA-3 is expressed on endothelial cells at low levels. The CD2/LFA-3 complex is an adhesion mechanism distinct from the LFA-1/ICAM-1 system, and binding of erythrocyte LFA-3 to T-lymphocyte CD2 is the basis of E-rosetting.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

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