leukaemia
(= leukemia (USA) )
Malignant neoplasia of leucocytes. Several different types are recognized according to the stem cell that has been affected, and several virus-induced leukaemias are known (eg. that caused by feline leukaemia virus). Both acute and chronic forms occur: (1) Acute lymphoblastic leukaemia (ALL) - neoplastic proliferation of white cell precursors in which the blood has large numbers of primitive lymphocytes (high nuclear/cytoplasmic ratio characteristic of dividing cells and few specific surface antigens expressed) ; tends to be common in the young;
(2) Acute myeloblastic leukaemia (AML) - more common in adults; the proliferating cells are of the myeloid haematopoietic series and the cells appearing in the blood are primitive granulocytes or monocytes;
(3) Chronic lymphocytic leukaemia (CLL) - neoplastic disease of middle or old age, characterized by excessive numbers of circulating lymphocytes of normal, mature appearance, usually B-lymphocytes; presumably a neoplastic transformation of lymphoid stem cells;
(4) Chronic myelogenous leukaemia (CML) - neoplasia of myeloid stem cells, commonest in middle-aged or elderly people, characterized by excessive numbers of circulating leucocytes, most commonly neutrophils (or precursors), but occasionally eosinophils or basophils.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Leukaemia — Leu*k[ae] mi*a (l[ u]*k[=e] m[i^]*[.a]), n. Leucocyth[ae]mia. [1913 Webster] …   The Collaborative International Dictionary of English

  • leukaemia — alternative spelling of LEUKEMIA (Cf. leukemia) …   Etymology dictionary

  • leukaemia — is the spelling for the disease in BrE, and leukemia in AmE …   Modern English usage

  • leukaemia — (US leukemia) ► NOUN ▪ a malignant progressive disease in which the bone marrow and other blood forming organs produce increased numbers of immature or abnormal white cells, suppressing the production of normal blood cells. DERIVATIVES leukaemic… …   English terms dictionary

  • leukaemia — n. any of a group of malignant diseases in which the bone marrow and other blood forming organs produce increased numbers of certain types of white blood cells (leucocyte). Overproduction of these white cells, which are immature or abnormal forms …   Medical dictionary

  • leukaemia — n. 1) to develop leukaemia 2) to have, suffer from leukaemia 3) acute leukaemia * * * [l(j)uː kiːmɪə] acute leukaemia to develop leukaemia to have. suffer from leukaemia …   Combinatory dictionary

  • leukaemia — n. any of a group of malignant diseases in which the bone marrow and other blood forming organs produce increased numbers of certain types of white blood cells (leucocytes). Overproduction of these white cells, which are immature or abnormal… …   The new mediacal dictionary

  • leukaemia — (BrE) (AmE leukemia) noun ADJECTIVE ▪ childhood ▪ acute, chronic VERB + LEUKAEMIA/LEUKEMIA ▪ have, suffer from …   Collocations dictionary

  • leukaemia — [[t]luki͟ːmiə[/t]] N UNCOUNT Leukaemia is a disease of the blood in which the body produces too many white blood cells. (in AM, use leukemia) …   English dictionary

  • leukaemia — Leuchaemia Leu*ch[ae] mi*a (l[ u]*k[=e] m[i^]*[.a]), n. [NL., fr. Gr. leyko s white + a i^ma blood.] (Med.) See {Leucocyth[ae]mia}. {Leu*ch[ae]m ic} (l[ u]*k[e^]m [i^]k), a. [Written also {leuk[ae]mia}, {leuk[ae]mic}.] [1913 Webster] …   The Collaborative International Dictionary of English

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