leader sequence


leader sequence
In the regulation of gene expression for enzymes concerned with amino acid synthesis in prokaryotes, the leader sequence codes for the leader peptide that contains several residues of the amino acid being regulated. Transcription is closely linked to translation, and if translation is retarded by limited supply of aminoacyl tRNA for the specific amino acid, the mode of transcription of the leader sequence permits full transcription of the operon genes; otherwise complete transcription of the leader sequence prematurely terminates transcription of the operon.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Leader sequence — may refer to: * Leader sequence (mRNA), a sequence of mRNA * Leading strand, in DNA replication …   Wikipedia

  • leader sequence — leader sequence. См. лидерная последовательность. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • leader sequence — A nontranslated sequence at the 5 end of mRNA that lies between the operator and the initiation codon; it aids in the initiation and regulation of transcription …   Dictionary of microbiology

  • leader sequence — noun The sequence at the 5 end of an mRNA molecule that is not translated into protein …   Wiktionary

  • leader sequence — A variable length sequence of nucleotides at the 5 end of an mRNA molecule that precedes the AUG initiation codon where translation begins and is not itself translated into protein …   Glossary of Biotechnology

  • leader sequence — signal s …   Medical dictionary

  • leader sequence peptide — leader sequence peptide. См. сигнальная последовательность. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • PelB leader sequence — The pelB leader sequence is a sequence of amino acids which when attached to a protein, directs the protein to the periplasmic membrane of E. coli , where the sequence is removed by pelB peptidase. It is used to direct coat protein antigen… …   Wikipedia

  • leader peptide — See leader sequence …   Dictionary of molecular biology

  • Sequence (filmmaking) — In film, a sequence is a series of scenes which form a distinct narrative unit, usually connected either by unity of location or unity of time. For example a heist film might include an extended recruitment sequence in which the leader of the… …   Wikipedia


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