Langhans' giant cells


Langhans' giant cells
Multinucleate cells formed by fusion of epithelioid macrophages and associated with the central part of early tubercular lesions. Similar to foreign body giant cells, but with the nuclei peripherally located.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Langhans giant cells — giant cells that resemble foreign body giant cells but have their nuclei arranged in a circle or a horseshoe shaped pattern at the periphery, often seen in granulomatous inflammation …   Medical dictionary

  • Langhans giant cell — Langhans giant cells are large cells found in granulomatous conditions. They are formed by the fusion of epithelioid cells (macrophages), and contain nuclei arranged in a horseshoe shaped pattern in the cell periphery. Their presence could… …   Wikipedia

  • Langhans giant cell — n any of the large cells found in the lesions of some granulomatous conditions (as leprosy and tuberculosis) and containing a number of peripheral nuclei arranged in a circle or in the shape of a horseshoe …   Medical dictionary

  • Giant cell — Multinucleated giant cells due to an infection. H E stain. A giant cell is a mass formed by the union of several distinct cells (usually macrophages).[1] It can arise in response to an infection or foreign body. Types include: foreign body giant… …   Wikipedia

  • giant cell — ▪ pathology also called  Langhans giant cell        large cell characterized by an arc of nuclei (nucleus) toward the outer membrane. The cell is formed by the fusion of epithelioid cells, which are derived from immune cells called macrophages.… …   Universalium

  • giant cell — gi·ant cell jī ənt n an unusually large cell esp a large multinucleate often phagocytic cell (as those characteristic of tubercular lesions, various sarcomas, or the megakaryocytes of the red marrow) * * * any large cell, such as a megakaryocyte …   Medical dictionary

  • Langhans cell — Lang·hans cell läŋ .hän(t)s n any of the cells of cuboidal epithelium that make up the cytotrophoblast Langhans Theodor (1839 1915) German pathologist and anatomist. Langhans described the cytotrophoblast and the cells that form it in 1870. He is …   Medical dictionary

  • Langhans — Theodor, German pathologist, 1839–1915. See L. cells, under cell, L. type giant cells, under cell, L. layer, L. stria …   Medical dictionary

  • Theodor Langhans — (September 28, 1839 October 22, 1915) was a German pathologist who was a native of Usingen, Hesse. He studied medicine at the University of Heidelberg, and in Gottingen under Friedrich Gustav Jakob Henle (1809 1885), at Berlin under Rudolf… …   Wikipedia

  • foreign body giant cell — Syncytium formed by the fusion of macrophages in response to an indigestible particle too large to be phagocytosed (eg. talc, silica or asbestos fibres). There may be as many as 100 nuclei randomly distributed: similar cells but with the nuclei… …   Dictionary of molecular biology


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