lamins


lamins
Proteins that form the nuclear lamina, a polymeric structure intercalated between chromatin and the inner nuclear envelope. Lamins A and C (70 and 60 kD respectively) have C-terminal sequences homologous to the head and tail domains of keratins; their peptide maps are similar, and significantly different from that of lamin B (67 kD), although there are some common epitopes.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • lamins — Fibrous network associated with the inner membranes of cell nuclei, composed of polypeptides of varying molecular weights (60,000–80,000) and classified as A, B, C, etc. on the basis of physical properties; the phosphorylation of l. is associated …   Medical dictionary

  • Nuclear lamina — The nuclear lamina is a dense ( 30 to 100 nm thick) fibrillar network inside the nucleus of a eukaryotic cell. It is composed of intermediate filaments and membrane associated proteins. Besides providing mechanical support, the nuclear lamina… …   Wikipedia

  • Cell nucleus — HeLa cells stained for the cell nucleus DNA with the Blue Hoechst dye. The central and rightmost cell are in interphase, thus their entire nuclei are labeled. On the left, a cell is going through mitosis and its DNA has condensed ready for… …   Wikipedia

  • Lamin — Nuclear lamins, also known as Class V intermediate filaments, are fibrous proteins providing structural function and transcriptional regulation in the cell nucleus. Nuclear lamins interact with membrane associated proteins to form the nuclear… …   Wikipedia

  • Intermediate filament — Intermediate filaments (IFs) are cytoskeletal structures formed by members of a family of related proteins called keratin. Intermediate filaments have a diameter of 12 nanometers, which is between that of actin (microfilaments) and microtubules.… …   Wikipedia

  • LMNA — Lamin A/C PDB rendering based on 1ifr …   Wikipedia

  • Laminopathy — Normal nuclear lamina (a and b) and mutant nuclear lamina (c and d) from a patient with HGPS, visualized by immunofluorescence note the irregular and bumpy shape of the laminopathic nuclei[1] Laminopathies are a group of rare genetic disorders… …   Wikipedia

  • LMNB1 — Lamin B1, also known as LMNB1, is a human gene.cite web | title = Entrez Gene: LMNB1 lamin B1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=4001| accessdate = ] PBB Summary section title = summary text =… …   Wikipedia

  • Núcleo celular — Células HeLa teñidas mediantes la tinción de Hoechst, que marca en azul el ADN. La célula central y la última de la der …   Wikipedia Español

  • Lamina (Zellkern) — Die im eukaryotischen Zellkern enthaltene Lamina ist ein dichter, fibrillärer Verbund, der weitgehend direkt unter der Kernhülle liegt und etwa 30 bis 100nm stark ist. Sie enthält Intermediärfilamente und Proteine, die mit der inneren Membran der …   Deutsch Wikipedia


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.