lactose repressor


lactose repressor
Protein (tetramer of 37 kD subunits) that normally binds with very high affinity to the operator region of the lactose operon and inhibits transcription of the downstream genes by blocking access of the polymerase to the promoter region. When the lactose repressor binds allolactose, its binding to the operator is reduced and the gene set is derepressed.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • lactose operon — Group of adjacent and coordinately controlled genes concerned with the metabolism of lactose in E. coli. The lac operon was the first example of a group of genes under the control of an operator region to which a lactose repressor binds. When the …   Dictionary of molecular biology

  • repressor protein — A protein that binds to an operator of a gene preventing the transcription of the gene. The binding affinity of repressors for the operator may be affected by other molecules. Inducers bind to repressors and decrease their binding to the operator …   Dictionary of molecular biology

  • Lactose-Operon — Das Lactose Operon, kurz lac Operon, ist ein Operon, das sowohl beim Transport, als auch beim Abbau von Lactose in Bakterien, beispielsweise Escherichia coli, eine wichtige Rolle spielt. Inhaltsverzeichnis 1 Aufbau des Operons 2 Regulation des… …   Deutsch Wikipedia

  • Repressor — Als Repressor bezeichnet man in der Genetik ein DNA bindendes Regulator Protein, welches an den Operator bindet und damit die Bindung der RNA Polymerase an den Promotor blockiert, wodurch die Transkription des Gens (oder Operons) verhindert wird …   Deutsch Wikipedia

  • Lac repressor — [ http://www.pdb.org/pdb/static.do?p=education discussion/molecule of the month/pdb39 1.html more details...] ] The lac repressor is a DNA binding protein which inhibits the expression of genes coding for proteins involved in the metabolism of… …   Wikipedia

  • LacR — lactose repressor …   Medical dictionary

  • LacR — • lactose repressor …   Dictionary of medical acronyms & abbreviations

  • Lac operon — The lac operon is an operon required for the transport and metabolism of lactose in Escherichia coli and some other enteric bacteria. It consists of three adjacent structural genes, a promoter, a terminator, and an operator. The lac operon is… …   Wikipedia

  • CAP — (= catabolite gene activator protein) Protein from E. coli that regulates the expression of genes for the use of alternative carbon sources if glucose is not available. For example, CAP and the lactose repressor protein act together to enable… …   Dictionary of molecular biology

  • Iac-Operon — Das Lactose Operon, kurz lac Operon, ist ein Operon, das sowohl beim Transport, als auch beim Abbau von Lactose in Bakterien, beispielsweise Escherichia coli, eine wichtige Rolle spielt. Inhaltsverzeichnis 1 Aufbau des Operons 2 Regulation des… …   Deutsch Wikipedia


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