killer cells

killer cells
(= K cells)
(1) Mammalian cells which can lyse antibody-coated target cells. They have a receptor for the Fc portion of IgG, and are probably of the mononuclear phagocyte lineage, though some may be lymphocytes. Not to be confused with cytotoxic T-cells (CTL) which recognize targets by other means and are clearly a subset of T-lymphocytes: this confusion exists in the early literature.
(2) (NK cells) Natural killer cells are CD3-negative large granular lymphocytes, mediating cytolytic reactions that do not require expression of Class I or II major histocompatibility antigens on the target cell.
(3) (LAK cells) Lymphokine-activated killer cells are NK cells activated by interleukin-2.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • killer cells — 1. K c s (def. 1). 2. cytotoxic T lymphocytes …   Medical dictionary

  • lymphokine-activated killer cells — killer cells activated by interleukin 2 that have specificity towards tumors refractory to NK cells; they may represent a further activation state of the NK cell. Called also LAK c s …   Medical dictionary

  • natural killer cells — (= NK cells) See killer cells …   Dictionary of molecular biology

  • natural killer cells — NK c s …   Medical dictionary

  • T-killer cells — cytotoxic T lymphocytes …   Medical dictionary

  • Killer sudoku — (also killer su doku, sumdoku, sum doku, addoku, or samunamupure) is a puzzle that combines elements of sudoku and kakuro. Despite the name, the simpler killer sudokus can be easier to solve than regular sudokus, depending on the solver s skill… …   Wikipedia

  • Killer yeasts — are yeasts, such as Saccharomyces cerevisiae , which can carry a double stranded RNA virus, causing them to secrete a number of toxic proteins which are lethal to receptive cells.cite journal|author=Young, T. W. Yagiu, M.|date=1978|title=A… …   Wikipedia

  • Killer-cell immunoglobulin-like receptor — Killer cell immunoglobulin like receptors (KIRs), are a family of cell surface proteins found on important cells of the immune system called natural killer (NK) cells. They regulate the killing function of these cells by interacting with MHC… …   Wikipedia

  • killer cell — n. any of various cells that destroy germs, infected cells, etc.; esp., a lymphocyte (killer T cell) that destroys infected or cancerous cells by releasing proteins that damage the cell membranes of the target cells …   English World dictionary

  • killer T cell — noun T cell with CD8 receptor that recognizes antigens on the surface of a virus infected cell and binds to the infected cell and kill it • Syn: ↑killer cell, ↑cytotoxic T cell, ↑CD8 T cell, ↑CD8 cell • Hypernyms: ↑T cell, ↑T lymphocyte * * * …   Useful english dictionary


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.