(= IL-12; NK stimulatory factor; cytotoxic lymphocyte maturation factor)Heterodimeric cytokine (35 kD and 40 kD) that enhances the lytic activity of NK cells, induces interferon- gproduction, stimulates the proliferation of activated T-cells and NK cells. Is secreted by human B-lymphoblastoid cells (NC-37). May play a role in controlling immunoglobulin isotype selection and is known to inhibit IgE production.
Dictionary of molecular biology. 2004.
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