initiation factors


initiation factors
The set of catalytic proteins required, in addition to mRNA and ribosomes, for protein synthesis to begin. In bacteria three distinct proteins have been identified: IF-1 (8 kD),IF-2 (75 kD) and IF-3 (30 kD). At least 6-8 proteins have been identified in eukaryotes. IFs 1 and 2 enhance the binding of initiator tRNA to the initiation complex.

Dictionary of molecular biology. 2004.

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  • initiation factors — initiation factors. См. факторы инициации. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Prokaryotic initiation factors — Prokaryotes require the use of three initiation factors: IF1, IF2, and IF3, for translation. IF1 IF1 associates with the 30S ribosomal subunit in the A site and prevents an aminoacyl tRNA from entering. It modulates IF2 binding to the ribosome by …   Wikipedia

  • Initiation factor — Initiation factors are proteins that bind to the small subunit of the ribosome during the initiation of translation, a part of protein biosynthesis.They are divided into two major groups: * Prokaryotic initiation factors * Eukaryotic initiation… …   Wikipedia

  • initiation complex — Complex between mRNA, 30S ribosomal subunit and formyl methionyl tRNA that requires GTP and initiation factors to function …   Dictionary of molecular biology

  • Eukaryotic initiation factor — Eukaryotic initiation factors are proteins used in eukaryotic translation. There exist many more eukaryotic initiation factors (eIF) than prokaryotic initiation factors due to greater biological complexity. Processes eIF is involved in include:… …   Wikipedia

  • Eukaryotic translation initiation factor 4 gamma — Eukaryotic translation initiation factor 4 gamma, 1, also known as EIF4G1, is a human gene. PBB Summary section title = summary text = The protein encoded by this gene is a component of the protein complex EIF4F, which is involved in the… …   Wikipedia

  • Acquisition Initiation (ISPL) — Acquisition initiation is the first process within the Information Services Procurement Library and is executed by the customer organization, intending to procure Information Services.Two main activities lie within this process: the making of the …   Wikipedia

  • Risk factors for breast cancer — Risk factors of breast cancer may be divided into preventable and non preventable. Their study belongs in the field of epidemiology. Breast cancer, like other forms of cancer, is considered to result from multiple environmental and hereditary… …   Wikipedia

  • Transcription initiation protein SPT3 homolog — Suppressor of Ty 3 homolog (S. cerevisiae), also known as SUPT3H, is a human gene.cite web | title = Entrez Gene: SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • факторы инициации — initiation factors факторы инициации. Белковые молекулы, связывающиеся с малой (30S) субчастицей рибосомы, необходимые для осуществления инициации белкового синтеза: Ф.и. входят в состав тройного комплекса <tertiary complex>; известно по… …   Молекулярная биология и генетика. Толковый словарь.


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