IgG
The classical immunoglobulin class also known as 7S IgG (150 kD). Composed of two identical light and two identical heavy chains, the constant region sequence of the heavy chains being of the g type. The molecule can be described in another way as being composed of two Fab and an Fcfragment. The Fabs include the antigen combining sites; the Fc region consists of the remaining constant sequence domains of the heavy chains and contains cell-binding and complement-binding sites. IgGs act on pathogens by agglutinating them, by opsonizing them, by activating complement-mediated reactions against cellular pathogens and by neutralising toxins. They can pass across the placenta to the foetus as maternal antibodies, unlike other Ig classes. In humans four main subclasses are known, IgG2 differs from the rest in not being transferred across the placenta and IgG4 does not fix complement. IgG is present at 8-16 mg/ml in serum.1. A23187

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • IgG — Abreviatura de inmunoglobulina G. Diccionario Mosby Medicina, Enfermería y Ciencias de la Salud, Ediciones Hancourt, S.A. 1999 …   Diccionario médico

  • IgG — IgG, IgM ↑ Immunglobulin …   Universal-Lexikon

  • IgG — räumliche Darstellung eines IgG Antikörpers Immunglobulin G (IgG) oder Gammaglobulin ist ein Glykoprotein, das von B Lymphozyten bzw. Plasmazellen nach Kontakt mit einem Antigen produziert wird. IgGs sind die Antikörper (Immunglobuline) der… …   Deutsch Wikipedia

  • Igg — räumliche Darstellung eines IgG Antikörpers Immunglobulin G (IgG) oder Gammaglobulin ist ein Glykoprotein, das von B Lymphozyten bzw. Plasmazellen nach Kontakt mit einem Antigen produziert wird. IgGs sind die Antikörper (Immunglobuline) der… …   Deutsch Wikipedia

  • IgG — Abbreviation for immunoglobulin G, a major class of immunoglobulins found in the blood, including many of the most common antibodies circulating in the blood. Also known as gamma globulin. * * * Abbreviation for immunoglobulin G. * * *… …   Medical dictionary

  • IgG — noun Date: 1965 1. a class of immunoglobulins including the most common antibodies circulating in the blood that facilitate the phagocytic destruction of microorganisms foreign to the body, that bind to and activate complement, and that are the… …   New Collegiate Dictionary

  • IgG — noun one of the five major classes of immunoglobulins; the main antibody defense against bacteria • Syn: ↑immunoglobulin G • Hypernyms: ↑immunoglobulin, ↑Ig, ↑immune serum globulin, ↑immune gamma globulin, ↑immune globulin * * * …   Useful english dictionary

  • IgG — см. Иммуноглобулины G …   Большой медицинский словарь

  • IgG — см. Иммуноглобулины G …   Медицинская энциклопедия

  • IgG — …   Википедия

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