hypervariable region


hypervariable region
Those regions of the heavy or light chains of immunoglobulins in which there is considerable sequence diversity within that set of immunoglobulins in a single individual. These regions specify the antigen affinity of each antibody.

Dictionary of molecular biology. 2004.

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  • hypervariable region — hypervariable region. См. гипервариабельный участок. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Hypervariable region — A hypervariable region (HVR) is a location within nuclear DNA or the D loop of mitochondrial DNA in which base pairs of nucleotides repeat (in the case of nuclear DNA) or have substitutions (in the case of mitochondrial DNA). Changes or repeats… …   Wikipedia

  • hypervariable region —    A segment of a chromosome characterized by considerable variation in the number of tandem repeats at one or more loci …   Forensic science glossary

  • hypervariable region — The parts of both the heavy and light chains of an antibody molecule that enable it to bind to a specific site on an antigen …   Glossary of Biotechnology

  • Hypervariable — may refer to:*Hypervariable sequence, a segment of a chromosome characterised by considerable variation in the number of tandem repeats at one or more loci *Hypervariable locus, a locus with many alleles; especially those whose variation is due… …   Wikipedia

  • region — 1. An often arbitrarily limited portion of the surface of the body. SEE ALSO: space, zone. 2. A portion of the body having a special nervous or vascular supply, or a part of an organ having a special …   Medical dictionary

  • hypervariable — hy·per·vari·able ver ē ə bəl, var adj relating to or being any of the relatively short polypeptide chain segments in the variable region of an antibody light chain or heavy chain that are extremely variable in the sequence of their amino acid… …   Medical dictionary

  • hypervariable segment — A region of a protein that varies considerably between strains or individuals …   Glossary of Biotechnology

  • hypervariable — ˌ adjective Etymology: hyper + variable (I) : relating to or being any of the relatively short polypeptide chain segments in the variable region of an antibody light chain or heavy chain that are extremely variable in the sequence of their amino… …   Useful english dictionary

  • mtDNA control region — Mitochondrial DNA control region secondary structure A The consensus secondary structure for all haplotypes of the mtDNA control region. Identifiers Symbol mtDNA ssA …   Wikipedia


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