Hodgkin's disease


Hodgkin's disease
A human lymphoma that appears to originate in a particular lymph node and later spreads to the spleen, liver and bone marrow. Giant cells, the Sternberg-Reed cells, with mirror-image nuclei are diagnostic. Immunological depletion, caused perhaps by the excessive growth of neoplastic histiocytes, occurs. Four types of the disease are recognized depending on the relative predominance of various neoplastic derivatives of the lymphoid series. Pyrexia is often a feature of the disease. Death often results from generalized immunological inability to respond to infections.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Hodgkin's disease — ► NOUN ▪ a malignant disease of lymphatic tissues typically causing enlargement of the lymph nodes, liver, and spleen. ORIGIN named after the English physician Thomas Hodgkin (1798 1866) …   English terms dictionary

  • Hodgkin's disease — [häj′kinz] n. [after Dr. T. Hodgkin (1798 1866), Eng physician who first described it] a chronic disease of unknown cause characterized by progressive enlargement of the lymph nodes and inflammation of other lymphoid tissues, esp. of the spleen …   English World dictionary

  • Hodgkin's disease — Hodg kin s dis*ease (Med.) A morbid condition characterized by progressive an[ae]mia and enlargement of the lymphatic glands; first described by Dr. Hodgkin, an English physician …   The Collaborative International Dictionary of English

  • Hodgkin's disease — 1877, named for Dr. Thomas Hodgkin (1798 1866) who first described it …   Etymology dictionary

  • Hodgkin's disease — Hodg·kin s disease häj kənz n a neoplastic disease that is characterized by progressive enlargement of lymph nodes, spleen, and liver and by progressive anemia Hodgkin Thomas (1798 1866) British physician. Hodgkin made important contributions in… …   Medical dictionary

  • Hodgkin's disease — a malignant disease of lymphatic tissue – a form of lymphoma – usually characterized by painless enlargement of one or more groups of lymph nodes in the neck, axillae (armpits), groin, chest, or abdomen; the spleen, liver, bone marrow, and bones… …   The new mediacal dictionary

  • Hodgkin's disease — noun Etymology: Thomas Hodgkin died 1866 English physician Date: 1865 a neoplastic disease that is characterized by progressive enlargement of lymph nodes, spleen, and liver and by progressive anemia called also Hodgkin s, Hodgkin s lymphoma …   New Collegiate Dictionary

  • Hodgkin's disease — /ˈhɒdʒkənz dəziz/ (say hojkuhnz duhzeez) noun a form of cancer involving the lymph glands whose symptoms sometimes include swellings, usually painless, of the lymph glands, especially those in the neck. Also, Hodgkin s lymphoma. {named after… …   Australian English dictionary

  • Hodgkin's disease —    Occasionally mispunctuated, as here: Two years later, he was found to be suffering from Hodgkins disease (Newsweek). The disease was first described by a British physician named Thomas Hodgkin …   Dictionary of troublesome word

  • Hodgkin's disease — noun a malignant disease of lymphatic tissues typically causing enlargement of the lymph nodes, liver, and spleen. Origin C19: named after the English physician Thomas Hodgkin …   English new terms dictionary

  • Hodgkin's disease — Hodg′kin s disease n. pat a malignant disorder characterized by enlargement of the lymph nodes and spleen and by lymphoid infiltration along the blood vessels • Etymology: 1860–65; after Thomas Hodgkin (1798–1866), London physician who described… …   From formal English to slang


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