helix-loop-helix


helix-loop-helix
A motif associated with transcription factors, allowing them to recognize and bind to specific DNA sequences. Two alpha-helices are separated by a loop. Examples: myoblast MyoD 1, c- myc, Drosophila genes daughterless, hairy, twist, scute, achaete, asense. Not the same as helix-turn-helix.

Dictionary of molecular biology. 2004.

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  • helix-loop-helix — helix loop helix. См. спираль петля спираль. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Helix-loop-helix-Transkriptionsfaktoren — sind ein Strukturmotiv DNA bindender Proteine, das aus einer kurzen α Helix besteht, die durch eine flexible Schleife (engl. loop) mit einer zweiten längeren Helix verknüpft ist. Dieses HLH Motiv unterscheidet sich vom Helix Turn Helix Motiv.… …   Deutsch Wikipedia

  • Basic-helix-loop-helix — A basic helix loop helix (bHLH) is a protein structural motif that characterizes a family of transcription factors. Structure The motif is characterized by two α helices connected by a loop. In general, transcription factors including this domain …   Wikipedia

  • Basic helix-loop-helix leucine zipper transcription factors — are, as their name indicates, transcription factors containing both Basic helix loop helix and leucine zipper motifs.An example is Microphthalmia associated transcription factor.External links* …   Wikipedia

  • Helix-turn-helix — In proteins, the helix turn helix (HTH) is a major structural motif capable of binding DNA. It is composed of two α helices joined by a short strand of amino acids and is found in many proteins that regulate gene expression. It should not to be… …   Wikipedia

  • helix-turn-helix — A motif associated with transcription factors, allowing them to bind to and recognize specific DNA sequences. Two amphipathic alpha helices are separated by a short sequence with a beta pleated sheet. One helix lies across the major groove of the …   Dictionary of molecular biology

  • loop — 1. noun a loop of rope Syn: coil, hoop, ring, circle, noose, oval, spiral, curl, bend, curve, arc, twirl, whorl, twist, hook, helix, convolution 2. verb 1) Dave l …   Thesaurus of popular words

  • loop — 1. noun a loop of rope Syn: coil, ring, circle, noose, spiral, curl, bend, curve, arc, twirl, whorl, twist, helix 2. verb 1) Dave looped rope around their hands Syn …   Synonyms and antonyms dictionary

  • helix — n spiral, screw, thread, corkscrew, whorl, twist, volute; coil, loop, ring, circumvolution; curl, curlicue, ringlet, tendril …   A Note on the Style of the synonym finder

  • loop — n 1. noose, bow, circle, ring, hoop; spiral, helix, convolution, whorl, coil, curl, twirl; arc, arch, curve, bend. v 2. roK furl, coil, wind; spiral, twirl, curl, curlicue, twist, kink; arc, arch, curve, bend, round, turn. 3. circle, encircle,… …   A Note on the Style of the synonym finder


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