Of a binding site in a protein, usually an enzyme. The catalytic function of an enzyme may be modified by interaction with small molecules, not only at the active site, but also at a spatially distinct (allosteric) site of different specificity. Of a protein, a protein possessing such a site. An allosteric effector is a molecule bound at such a site that increases or decreases the activity of the enzyme.
Dictionary of molecular biology. 2004.
Look at other dictionaries:
allosteric — [al΄ō ster′ik, al΄ōstir′ik; al΄əster′ik, al΄əstir′ik] adj. of or having to do with a protein with a structure that is altered reversibly by a small molecule so that its original function is modified … English World dictionary
allosteric — adjective Etymology: all + steric Date: 1962 of, relating to, undergoing, or being a change in the shape and activity of a protein (as an enzyme) that results from combination with another substance at a point other than the chemically active… … New Collegiate Dictionary
allosteric — allosterically, adv. /al euh ster ik, stear /, adj. Biochem. pertaining to regulation of the rate of an enzymatic process. [1960 65; ALLO + STERIC] * * * … Universalium
allosteric — adjective That binds a compound on an inactive site and thus changes conformation in order to become either active or inactive See Also: allostery … Wiktionary
allosteric — Pertaining to or characterized by allosterism. * * * al·lo·ste·ric .al ō ster ik, sti(ə)r adj of, relating to, or being a change in the shape and activity of a protein (as an enzyme) that results from combination with another substance at a point … Medical dictionary
allosteric — [ˌalə stɛrɪk, stɪərɪk] adjective Biochemistry relating to or denoting the alteration of the activity of an enzyme by means of a conformational change induced by a different molecule. Derivatives allosterically adverb … English new terms dictionary
allosteric — al·lo·ste·ric … English syllables
allosteric — al•lo•ster•ic [[t]ˌæl əˈstɛr ɪk, ˈstɪər [/t]] adj. biochem. of or pertaining to a change in the activity of an enzyme at a site other than the binding site of the substrate • Etymology: 1960–65 al lo•ster′i•cal•ly, adv. al lo•ster′ism … From formal English to slang
allosteric — … Useful english dictionary
Allosteric enzyme — Allosteric enzymes are enzymes that change their shape, or conformation, upon binding of a modulator. The word allosteric comes from the Greek allos, other and stereos , shape . An allosteric enzyme is an oligomer whose biological activity is… … Wikipedia