guanylate cyclase


guanylate cyclase
Enzyme catalysing the synthesis of guanosine 3\',5\'- cyclic monophosphate from guanosine 5\'-triphosphate (cyclic GMP (cGMP) is used as a second messenger in heart muscle and photoreceptor cells). The plasma membrane form of guanylate cyclase is an integral membrane protein with an extracellular receptor for eptide hormones, a transmembrane domain, a protein kinase-like domain, and a guanylate cyclase domain. Examples: sea urchin receptors for speract and resact; and atrial natriuretic peptide receptors. Two soluble forms of guanylate cyclase are also known, heterodimers of highly related subunits, 70-80 kD.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

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  • guanylate cyclase — ¦gwänəlˌāt noun Etymology: guanyl + ate (I) : an enzyme that catalyzes the formation of cyclic GMP from GTP …   Useful english dictionary

  • Guanylate cyclase activator — A guanylate cyclase activator (or GUCA ) is one of group of proteins which upregulates guanylate cyclase.It is also known as guanylate cyclase activating protein , with the abbreviation GCAP .Mutations can be associated with vision defects.cite… …   Wikipedia

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  • Adenylate cyclase — Adénylate cyclase Pour les articles homonymes, voir AC. Un exemple de cascade d activation après fixation de l épinép …   Wikipédia en Français

  • Adénylate Cyclase — Pour les articles homonymes, voir AC. Un exemple de cascade d activation après fixation de l épinép …   Wikipédia en Français

  • Adénylate cyclase — Pour les articles homonymes, voir AC. Adénylate cyclase …   Wikipédia en Français


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