growth-associated proteins


growth-associated proteins
(= GAPs)
Group of developmentally regulated polypeptides thought to be critical for the formation of neural circuitry. The acidic membrane phosphoprotein GAP-43 is synthesized and transported down regenerating and developing axons; pp46 localized in growth cone membranes during embryogenesis; B-50 in mature presynaptic membranes in the regulation of phosphotidylinositol turnover and F1 in the hippocampus during long-term potentiation, are now all known to be the same protein.

Dictionary of molecular biology. 2004.

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