growth factors
Polypeptide hormones that regulate the division of cells, for example EGF (epidermal growth factor), PDGF (platelet-derived GF), FGF (fibroblast GF). Insulin and somatomedin are also growth factors; the status of NGF (nerve growth factor) is more uncertain. Perturbation of growth factor production or of the response to growth factor is important in neoplastic transformation.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • growth factors — См. differentiation factors …   Dictionary of molecular biology

  • growth factors — Organic compounds that must be supplied in the diet for growth because they are essential cell components or precursors of such components and cannot be synthesized by the organism …   Dictionary of microbiology

  • bone growth factors — a group of growth factors that promote new bone formation. Bone morphogenic protein (BMP), a naturally occurring substance that induces osteoblast formation, has been genetically synthesized to form bone morphogenetic protein, which stimulates… …   The new mediacal dictionary

  • Hemopoietic growth factors — regulate the differentiation and proliferation of particular progenitor cells. Made available through recombinant DNA technology, they hold tremendous potential for medical uses when a person s natural ability to form blood cells is diminished or …   Wikipedia

  • transforming growth factors-β — transforming growth factors β. См. трансформирующие β факторы роста. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • transforming growth factors-β — transforming growth factors β. = activins (см.) (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • B cell growth factors — (BCGF) factors derived from T cells that stimulate B cells to proliferate in vitro but (unlike B cell differentiation factors) do not stimulate antibody secretion. Cf. B lymphocyte stimulatory f s …   Medical dictionary

  • insulinlike growth factors — (IGF) serum peptides with insulin like actions, formerly called somatomedins (q.v.). IGF I (formerly somatomedin C) is an important growth hormone–dependent mediator of cell growth and replication. IGF II (formerly somatomedin A) appears to be… …   Medical dictionary

  • hematopoietic growth factors — a group of substances with the ability to support hematopoietic colony formation in vitro, including erythropoietin, interleukin 3, and colony stimulating factors. All except erythropoietin stimulate mature cells, have overlapping capabilities to …   Medical dictionary

  • growth factor — n a substance (as a vitamin B12 or an interleukin) that promotes growth and esp. cellular growth * * * any of various chemicals, particularly polypeptides, that have a variety of important roles in the stimulation of new cell growth and cell… …   Medical dictionary

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