germ-line transformation


germ-line transformation
Micro-injection of foreign DNA into an early embryo, so that it becomes incorporated into the germ-line of the individual, and thus stably inherited in subsequent generations of transgenic organisms. Typically, the DNA would be a reporter gene or cDNA in a vector such as a transposon, that might also carry a visible marker gene (such as eye or coat colour), so that successful transformation could readily be detected.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

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