gene amplification


gene amplification
Selective replication of DNA sequence within a cell, producing multiple extra copies of that sequence. The best-known example occurs during the maturation of the oocyte of Xenopus, where the set (normally 500 copies) of ribosomal RNA genes is replicated some 4,000 times to give about 2 million copies.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Gene amplification — Making multiple copies of a gene. Repeated copying of a gene. Gene amplification plays a role in cancer cells. A tumor cell amplifies, or copies, DNA segments as a result of cell signals and sometimes environmental events. Amplification can occur …   Medical dictionary

  • gene amplification — geno pagausėjimas statusas T sritis augalininkystė apibrėžtis Geno kopijų skaičiaus padidėjimas. atitikmenys: angl. gene amplification rus. амплификация генов ryšiai: sinonimas – genų amplifikacija …   Žemės ūkio augalų selekcijos ir sėklininkystės terminų žodynas

  • gene amplification — gene′ amplifica tion n. 1) gen an increase in the frequency of replication of a DNA segment 2) lab such an increase induced by a polymerase chain reaction • Etymology: 1970–75 …   From formal English to slang

  • gene amplification — The selective production of multiple copies of one gene without a proportional increase in others …   Glossary of Biotechnology

  • gene amplification — 1. an increase in the frequency of replication of a DNA segment. 2. such an increase induced by a polymerase chain reaction. [1970 75] * * * …   Universalium

  • gene amplification — 1. an increase in the frequency of replication of a DNA segment. 2. such an increase induced by a polymerase chain reaction. [1970 75] …   Useful english dictionary

  • gene amplification technique — a term sometimes used to denote a nucleic acid amplification technique, although the segment of DNA or RNA undergoing amplification does not necessarily correspond to a single, entire gene …   Medical dictionary

  • Gene duplication — Schematic of a region of a chromosome before and after a duplication event Gene duplication (or chromosomal duplication or gene amplification) is any duplication of a region of DNA that contains a gene; it may occur as an error in homologous… …   Wikipedia

  • Amplification — Making multiple copies of a gene or of any sequence of DNA. Repeated copying of a piece of DNA. In amplification there is an increase in the number of copies of any particular piece of DNA. Gene amplification plays a role in cancer cells. A tumor …   Medical dictionary

  • amplification — /am pleuh fi kay sheuhn/, n. 1. the act of amplifying or the state of being amplified. 2. expansion of a statement, narrative, etc., as for rhetorical purposes: In the revision, the story underwent considerable amplification. 3. a statement,… …   Universalium


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