- Friend murine leukaemia virus
Murine leukaemia virus isolated by Charlotte Friend in 1956 whilst attempting to transmit the Erlich ascites tumour by cell-free extracts. Causes an unusual erythroblastosis-like leukaemia, in which anaemia is accompanied by large numbers of nucleated red cells in blood. Does not carry a host-derived oncogene, but seems to induce tumours by proviral insertion into specific regions of host genome.
Dictionary of molecular biology. 2004.