forskolin
(= colforsin)
Diterpene from the roots of Coleus forskohlii that stimulates adenylate cyclase and is often used in conjunction with inhibitors of phosphodiesterase to artificially increase intracellular levels of cAMP.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Forskolin — IUPAC name (3R,​4aR,​5S,​6S,​6aS,​10S,​10aR,​10bS) ​6,​10,​10b ​trihydroxy ​3,​4a,​7 …   Wikipedia

  • Forskolin — Strukturformel Allgemeines Name Forskolin Andere Namen …   Deutsch Wikipedia

  • forskolin — noun A labdane diterpene produced by the plant Coleus forskohlii; commonly used in the study and research of cell physiology …   Wiktionary

  • forskolin — A phorbol ester that binds to and activates protein kinase C, thus mimicking the actions of diacylglycerol. [fr. Coleus forskohlii, taxonomic name of botanical source] …   Medical dictionary

  • forskolin — A medicinal, diterpenoid, compound exclusive to plant roots and used in the preparation of drugs for the treatment of cardiomyopathy, glaucoma and certain cancers …   Glossary of Biotechnology

  • Adenylylcyclasen — Schematische Darstellung der Adenylylcyclase, eingebettet in die Zellmembran …   Deutsch Wikipedia

  • Colforsin — Systematic (IUPAC) name [(3R,4aR,5S,6S,6aS,10S,10aR,10bS) 5 acetyloxy 3 ethenyl 10,10b dihydroxy 3,4a,7,7,10a pentamethyl 1 oxo 5,6,6a,8,9,10 hexahydro 2H benzo[f]chromen 6 yl] 3 dimethylaminopropanoate Cl …   Wikipedia

  • GalP (protein) — GalP is an integral membrane protein present in Escherichia Coli (1, 2). It is a Galactose H+ symporter, of approximately 52Kda (3). Present on the inner membrane of the gram negative E. Coli, GalP displays sequence homology to the GLUT1… …   Wikipedia

  • Plectranthus barbatus — Indian Coleus Scientific classification Kingdom: Plantae (unranked) …   Wikipedia

  • Adenylate cyclase — (EC number|4.6.1.1, also known as adenylyl cyclase or AC) is a lyase enzyme.TypesThere are ten known adenylate cyclases in mammals:* * * * * * * * * *ReactionAdenylate cyclase catalyzes the conversion of ATP to 3 ,5 cyclic AMP (cAMP) and… …   Wikipedia

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