fibroblast growth factor


fibroblast growth factor
(= FGF; aFGF; bFGF; HBGF)
Also known as heparin-binding growth factor (HBGF). Acidic FGF (a-FGF, HBGF 1) and basic FGF (b-FGF, HBGF 2) are the two founder members of a family of structurally related growth factors for mesodermal and neuroectodermal cells. Both aFGF and bFGF lack a signal sequence and the pathway of release is unclear. In addition to their growth promoting activity FGFs play an important part in developmental signalling.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

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  • fibroblast growth factor — noun Date: 1974 any of several protein growth factors that stimulate the proliferation especially of endothelial cells and that promote angiogenesis …   New Collegiate Dictionary

  • fibroblast growth factor — noun : any of several protein growth factors that stimulate the proliferation especially of endothelial cells and that promote angiogenesis …   Useful english dictionary


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