ABC proteins
Membrane proteins involved in active transport or regulation of ion channel function and having an ATP binding cassette. Most examples are prokaryotic, but important eukaryotic examples are the P-glycoprotein (multidrug resistance transporter), the cystic fibrosis transmembrane conductance regulator (CFTR), and SUR.

Dictionary of molecular biology. 2004.

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  • ABC transporters — [ATP binding cassette] a large family of transport proteins, consisting of two transmembrane and two cytoplasmic domains, that use energy released by ATP hydrolysis to transport a variety of substances across cell membranes …   Medical dictionary

  • ATP-binding domain of ABC transporters — Pfam box Symbol = ABC tran Name = width = caption =Multidrug ABC transporter SAV1866, closed state Pfam= PF00005 InterPro= IPR003439 SMART= PROSITE = PDOC00185 SCOP = 1b0u TCDB = 3.A.1 OPM family= 17 OPM protein=2hyd PDB=PDB3|1vplA:29 210… …   Wikipedia

  • Transmembrane domain of ABC transporters — Pfam box Symbol = ABC membrane Name = ABC transporter transmembrane region width = caption = Pfam= PF00664 InterPro= IPR001140 SMART= PROSITE = PDOC00364 SCOP = 1pf4 TCDB = 3.A.1 OPM family= 18 OPM protein= 1pf4 PDB=ABC transporter transmembrane… …   Wikipedia

  • Cystic fibrosis transmembrane conductance regulator — (ATP binding cassette sub family C, member 7) NBD1 of human CFTR complexed with ATP. PDB rendering based on 1xmi …   Wikipedia

  • ATP-binding cassette transporter — ATP binding cassette transporters (ABC transporter) are members of a superfamily that is one of the largest, and most ancient families with representatives in all extant phyla from prokaryotes to humans. Ref|Jones2004. These are transmembrane… …   Wikipedia

  • P-glycoprotein — ATP binding cassette, sub family B (MDR/TAP), member 1 Crystallographic structure of the mouse MDR3 protein. The approximate positioning of the protein in the cell membrane is indicated by the blue (extracellular face) and red (cytoplasmic face)… …   Wikipedia

  • ABCG2 — ATP binding cassette, sub family G (WHITE), member 2 Identifiers Symbols ABCG2; ABC15; ABCP; BCRP; BCRP1; BMDP; CD338; CDw338; EST157481; MGC102821; MRX; MXR; MXR1 External IDs …   Wikipedia

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