- extrinsic pathway
Initiation of blood clotting as a result of factors released from damaged tissue, as opposed to contact with a foreign surface (the intrinsic pathway). Tissue thromboplastin (Factor III) in conjunction with Factor VII (proconvertin) will activate Factor X that, once activated, converts prothrombin to thrombin.
Dictionary of molecular biology. 2004.
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Tissue factor pathway inhibitor — (or TFPI) is a single chain polypeptide which can reversibly inhibit Factor Xa (Xa). While Xa is inhibited, the Xa TFPI complex can subsequently also inhibit the FVIIa TF complex.TFPI contributes significantly to the inhibition of Xa in vivo,… … Wikipedia
intrinsic pathway — See extrinsic pathway … Dictionary of molecular biology
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