experimental allergic encephalomyelitis


experimental allergic encephalomyelitis
An autoimmune disease that can be induced in various experimental animals by the injection of homogenized brain or spinal cord in Freund\'s adjuvant. The antigen appears to be a basic protein present in myelin, and the response is characterized by focal areas of lymphocyte and macrophage infiltration into the brain, associated with demyelination and destruction of the blood-brain barrier. Sometimes used as a model for demyelinating diseases, although whether this is entirely justifiable is not clear.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

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