error-prone repair


error-prone repair

Dictionary of molecular biology. 2004.

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  • repair — Restoration of diseased or damaged tissues naturally by healing processes or artificially, as by surgical means. [M.E., fr. O.Fr., fr. L. re paro, fr. re , back, again, + paro, prepare, put in order] chemical r. conversion of a free radical to a… …   Medical dictionary

  • DNA repair — For the journal, see DNA Repair (journal). DNA damage resulting in multiple broken chromosomes DNA repair refers to a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human… …   Wikipedia

  • Postreplication repair — is the repair of damage to the DNA that takes place after replication. Some example genes in humans include: BRCA2 and BRCA1 BLM NBS1 DNA damage prevents the normal enzymatic synthesis of DNA by the replication fork.[1][2][3][4] …   Wikipedia

  • DNA repair and recombination protein RAD54-like — RAD54 like (S. cerevisiae) Identifiers Symbols RAD54L; HR54; RAD54A; hHR54; hRAD54 External IDs …   Wikipedia

  • Non-homologous end joining — (NHEJ) is a pathway that repairs double strand breaks in DNA. NHEJ is referred to as non homologous because the break ends are directly ligated without the need for a homologous template, in contrast to homologous recombination, which requires a… …   Wikipedia

  • SOS response — The SOS response is a postreplication DNA repair system that allows DNA replication to bypass lesions or errors in the DNA. The SOS uses the RecA protein. The RecA protein, stimulated by single stranded DNA, is involved in the inactivation of the …   Wikipedia

  • SOS system — The DNA repair system also known as error prone repair in which apurinic DNA molecules are repaired by incorporation of a base that may be the wrong base but that permits replication. RecA protein is required for this type of repair. SOS genes… …   Dictionary of molecular biology

  • Mutagenesis — (pronounced /mjuːtəˈdʒɛnɪsɪs/) is a process by which the genetic information of an organism is changed in a stable manner, resulting in a mutation. It may occur spontaneously in nature, or as a result of exposure to mutagens. It can also be… …   Wikipedia

  • DNA polymerase — 3D structure of the DNA binding helix turn helix motifs in human DNA polymerase beta A DNA polymerase is an enzyme that helps catalyze in the polymerization of deoxyribonucleotides into a DNA strand. DNA polymerases are best known for their… …   Wikipedia

  • Microhomology-mediated end joining — (MMEJ) is one of the pathways for repairing double strand breaks in DNA. Two other well known means of double strand breakage repair are non homologous end joining and homologous recombination. MMEJ is distinguished from the other repair… …   Wikipedia


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