epothilones
Compounds (epothilone A and B) isolated from myxobacterium Sorangium cellulosum Str 90. Cytotoxic to tumour cells as a result of inducing microtubule assembly and stabilization.

Dictionary of molecular biology. 2004.

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  • Epothilone — The epothilones are a new class of cytotoxic molecules identified as potential chemotherapeutic drugs. [Vincent T. DeVita, Jr., MD; Samuel Hellman, MD; and Steven A. Rosenberg, MD, PhD (2004) Cancer: Principles And Practice Of Oncology (7th… …   Wikipedia

  • Discovery and development of tubulin inhibitors — Tubulin inhibitors interfere directly with the tubulin system which is in contrast to those drugs acting on DNA for cancer chemotherapy. Microtubules play an important role in eukaryotic cells. Alpha and beta tubulin, the main components of… …   Wikipedia

  • Epothilone — Épothilone strucutre d un épothilone Les épothilones sont une nouvelle classe de molécules cytotoxiques, comprenant l épothilone A, l épothilone B, et l épothilone D, ayant un potentiel en tant que traitement chimiothérapeutique. Leur mécanisme d …   Wikipédia en Français

  • Épothilone — strucutre d un épothilone Les épothilones sont une nouvelle classe de molécules cytotoxiques, comprenant l épothilone A, l épothilone B, et l épothilone D, ayant un potentiel en tant que traitement chimiothérapeutique. Leur mécanisme d action est …   Wikipédia en Français

  • Organoboron chemistry — Organoboron Organoborane or organoboron compounds are chemical compounds that are organic derivatives of BH3, for example trialkyl boranes. Organoboron chemistry or organoborane chemistry is the chemistry of these compounds.[1] …   Wikipedia

  • Organoborane — PropertiesThe C B bond has low polarity (the difference in electronegativity 2.55 for carbon and 2.04 for boron) and therefore alkyl boron compounds are in general stable though easily oxidized. Vinyl groups and aryl groups donate electrons and… …   Wikipedia

  • Epothilon — Epothilone sind 16 gliedrige Macrolactone, die 1987 erstmals aus dem Myxobakterium Sorangium cellulosum von G. Höfle und H. Reichenbach an der ehemaligen Braunschweiger Gesellschaft für Biotechnologische Forschung (GBF, heute Helmholtz Zentrum… …   Deutsch Wikipedia

  • Epothilone — sind 16 gliedrige Macrolactone, die 1987 erstmals aus dem Myxobakterium Sorangium cellulosum von G. Höfle und H. Reichenbach an der ehemaligen Braunschweiger Gesellschaft für Biotechnologische Forschung (GBF, heute Helmholtz Zentrum für… …   Deutsch Wikipedia

  • Compuesto de organoboro — Estructura general de un organoborano donde R es un radical orgánico. Los compuestos de organoboro u organoboranos son compuestos químicos orgánicos derivados del BH3, por ejemplo, los trialquilboranos. La química de los compuestos de organoboro… …   Wikipedia Español

  • Chemotherapy — A woman being treated with docetaxel chemotherapy for breast cancer. Cold mittens and wine coolers are placed on her hands and feet to reduce harm to her nails. Chemotherapy (sometimes cancer chemotherapy) is the treatment of cancer with an… …   Wikipedia

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