Toxins from the American funnel web spider, Agalenopsis aperta. The m -toxins are 36-38 residue peptides that act on insect but not vertebrate voltage-sensitive sodium channels. The w -agatoxins are more diverse (5-9 kD) and act on various calcium channels, mostly in neuronal cells, blocking release of neurotransmitters. Affect vertebrate and invertebrate channels.
Dictionary of molecular biology. 2004.