dosage compensation
Genetic mechanisms that allow genes to be expressed at a similar level irrespective of the number of copies at which they are present. Usually invoked for genes that lie on sex chromosomes, that are thus present in different copy numbers in males and females.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Dosage compensation — Dosage compensation, also known as Ohno s Hypothesis, is a hypothetical genetic regulatory mechanism which operates to equalize the phenotypic expression of characteristics determined by genes on the X chromosome so that they are equally… …   Wikipedia

  • dosage compensation — dosage compensation. См. компенсация дозы [генов]. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • dosage compensation — n the genetic mechanism by which the same effect on the phenotype is produced by a pair of identical sex linked genes in the sex (as the human female) having the two sex chromosomes of the same type as by a single gene in the sex (as the human… …   Medical dictionary

  • dosage compensation — A regulatory mechanism for sex linked genes, to allow equivalent levels of gene expression from (in mammals) XY or XX genotypes, even though the gene copy number in XX is double that in XY. See: sex linkage, Barr body …   Glossary of Biotechnology

  • dosage compensation — noun : the genetic mechanism by which the same effect on the phenotype is produced by a pair of identical sex linked genes in the sex (as the human female) having the two sex chromosomes of the same type as by a single sex linked gene in the sex… …   Useful english dictionary

  • autosomal dosage compensation — autosomal dosage compensation. См. аутосомная компенсация дозы [гена]. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • compensation — 1. A process in which a tendency for a change in a given direction is counteracted by another change so that the original change is not evident. 2. An unconscious mechanism by which one tries to make up for fancied or real deficiencies. [L. com… …   Medical dictionary

  • компенсация дозы [генов] — dosage compensation компенсация дозы [генов]. Mеханизм регуляции экспрессии генов, сцепленных с полом; при механизме определения пола ХХ ХY у самок К.д. связана с инактивацией одной из Х хромосом <X inactivation> (при полисомии… …   Молекулярная биология и генетика. Толковый словарь.

  • Drosophila roX RNA — Drosophila roX1 ncRNA Conserved secondary structure of roX1 RNA Identifiers Symbol roX1 Rfam …   Wikipedia

  • X-inactivation — The Barr body is indicated by the arrow, it identifies the inactive X (Xi).] macroH2A1 staining. Arrow points to sex chromatin in DAPI stained cell nucleus, and to the corresponding sex chromatin site in the histone macroH2A1 staining.] X… …   Wikipedia

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