DH domain
(= Dbl homology domain)
Domain of around 250 amino acids found in Dbl, Vav and a family of other Dbl-family proteins (Lfc, Lsc, Ect2, Dbs, Brx). DH domains are invariably located immediately N-terminal to PH domain and the membrane localization and enzymatic activity of the DH domain requires the PH domain for normal function.

Dictionary of molecular biology. 2004.

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