decay accelerating factor
Plasma protein that regulates complement cascade by blocking the formation of the C3bBb complex (the C3 convertase of the alternate pathway). Widely distributed in tissues but deficient in paroxysmal nocturnal haemoglobinuria.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Decay accelerating factor — (CD55) is a 70 kDa membrane protein that regulates the complement system on the cell surface. It prevents the assembly of the C3bBb complex (the C3 convertase of the alternative pathway) or accelerates the disassembly of preformed convertase,… …   Wikipedia

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  • Alternative complement pathway — The classical and alternative complement pathways. Alternative pathway …   Wikipedia

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