cycloheximide
Antibiotic (MW 281) isolated from Streptomyces griseus. Blocks eukaryotic (but not prokaryotic) protein synthesis by preventing initiation and elongation on 80S ribosomes. Commonly used experimentally.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Cycloheximide — IUPAC name 4 [(2R) 2 [(1S,3S,5S) 3,5 Dimethyl 2 oxocyclohexyl] 2 hydroxyethyl]piperidine 2,6 dione …   Wikipedia

  • Cycloheximide — Général Nom IUPAC 4 {(2R) 2 [(1S,3S,5S) 3,5 dimethyl 2 oxocyclohexyl] 2 hydroxyethyl}piperidine 2,6 dione …   Wikipédia en Français

  • cycloheximide — cycloheximide. См. циклогексимид. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • cycloheximide — noun Etymology: cyclohexane + imide Date: 1950 an agricultural fungicide C15H23NO4 that inhibits protein synthesis and is obtained from a soil bacterium (Streptomyces griseus) …   New Collegiate Dictionary

  • cycloheximide — /suy kloh hek seuh muyd , mid/, n. Pharm. an antibiotic substance, C15H23NO4, isolated from the bacterium Streptomyces griseus, used experimentally to block protein synthesis. [1945 50; CYCLOHEX(ANE) + IMIDE] * * * …   Universalium

  • cycloheximide — noun an agricultural fungicide …   Wiktionary

  • cycloheximide — An antibiotic obtained from certain strains of Streptomyces griseus; used in biochemical research to inhibit in vitro protein synthesis; also a fungicide and rat repellent. * * * cy·clo·hex·i·mide hek sə .mīd, məd n an agricultural fungicide… …   Medical dictionary

  • cycloheximide — cy·clo·hex·i·mide …   English syllables

  • cycloheximide — A molecule that inhibits protein synthesis in eukaryotes, but not in prokaryotes. It blocks peptide bond formation by binding to the large ribosomal subunits. Synonym: actidione …   Glossary of Biotechnology

  • cycloheximide — ˌ ̷ ̷ ̷ ̷ˈheksəˌmīd, mə̇d noun ( s) Etymology: cyclohexanone + imide : a colorless crystalline antibiotic C15H23NO4 isolated from streptomycin producing strains of a soil bacterium (Streptomyces griseus) that is effective against several yeasts… …   Useful english dictionary

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