CpG island
(= CG island)
Region of genomic DNA rich in the dinucleotide C-G. Methylation of the C in the dinucleotide is maintained through cell divisions, and profoundly affects the degree of transcription of the nearby genes, and is important in developmental regulation of gene expression.There are around 30,000 CpG islands in a typical mammalian genome, and these tend to be undermethylated and upstream of housekeeping genes.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • CpG island — cytosine …   Wikipedia

  • CpG — can be: CpG site methylated sequences of DNA significant in gene regulation CpG Oligodeoxynucleotide unmethylated sequences of DNA that have immunostimulatory properties CpG island regions of DNA that contain several CpG sites This disambiguation …   Wikipedia

  • CpG site — Cytosine Phospha …   Wikipedia

  • CG island — (= CpG island) Region of genomic DNA rich in CG dinucleotides. Frequently found near genes that are transcribed at high level …   Dictionary of molecular biology

  • New Brighton, Staten Island — View of Brighton, Staten Island, New York, an 1857 engraving New Brighton, formerly an independent village, is today a neighborhood located on the North Shore of Staten Island in New York City, USA. The neighborhood comprises an older industrial… …   Wikipedia

  • Gola Island — Infobox Irish Place name = Gola Island gaeilge = Gabhla map pin coords = left: 37px; top: 42px north coord = 55.050941 | west coord = 8.235626 | irish grid = B847228 area = | elevation = province = Ulster county = County Donegal rural pop = 0… …   Wikipedia

  • Methylation — In the chemical sciences, methylation denotes the addition of a methyl group to a substrate or the substitution of an atom or group by a methyl group. Methylation is a form of alkylation with, to be specific, a methyl group, rather than a larger… …   Wikipedia

  • DNA methylation — Illustration of a DNA molecule that is methylated at the two center cytosines. DNA methylation plays an important role for epigenetic gene regulation in development and disease. DNA methylation is a biochemical process that is important for… …   Wikipedia

  • MECP2 — Methyl CpG binding protein 2 (Rett syndrome) PDB rendering based on 1qk9 …   Wikipedia

  • Methylated DNA immunoprecipitation — (MeDIP or mDIP) is a large scale (chromosome or genome wide) technique that is used to enrich for methylated DNA sequences. It consists of isolating methylated DNA fragments via an antibody raised against 5 methylcytosine (5mC). This technique… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”