contact inhibition of growth

Dictionary of molecular biology. 2004.

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  • density dependent inhibition of growth — The phenomenon exhibited by most normal (anchorage dependent) animal cells in culture that stop dividing once a critical cell density is reached. The critical density is considerably higher for most cells than the density at which a monolayer is… …   Dictionary of molecular biology

  • Contact inhibition — is the natural process of arresting cell growth when two or more cells come into contact with each other. Oncologists use this property to distinguish between normal and cancerous cells. Cell lines used widely in animal cell culture laboratories… …   Wikipedia

  • contact inhibition — n cessation of cellular undulating movements upon contact with other cells with accompanying cessation of cell growth and division * * * the inhibition of cell division and motility in normal cells when in close contact with each other, as in the …   Medical dictionary

  • contact inhibition — noun : cessation of cellular undulating movements upon contact with other cells with accompanying cessation of cell growth and division * * * Biol. the cessation of movement, growth, and division in cells that touch each other. [1960 65] * * *… …   Useful english dictionary

  • contact inhibition — noun Date: 1965 cessation of cellular movement, growth, and division upon contact with other cells …   New Collegiate Dictionary

  • contact inhibition — Biol. the cessation of movement, growth, and division in cells that touch each other. [1960 65] * * * …   Universalium

  • growth — /grohth/, n. 1. the act or process, or a manner of growing; development; gradual increase. 2. size or stage of development: It hasn t yet reached its full growth. 3. completed development. 4. development from a simpler to a more complex stage:… …   Universalium

  • Contact normalization — is a process by which intercellular junctions mediate signals that allow normal cells to inhibit the transformed growth of neighboring tumor cells. Intimate junctional contact between tumor cells and normal cells is needed for this form of growth …   Wikipedia

  • inhibition — 1. Depression or arrest of a function. SEE ALSO: inhibitor. 2. In psychoanalysis, the restraining of instinctual or unconscious drives or tendencies, especially if they conflict with one s conscience or with societal demands. 3. In psychology, a… …   Medical dictionary

  • monolayering of cells — Tendency of animal tissue cells growing on solid surfaces to cover the surface with a complete layer only one cell thick, before growing on top of each other. This non random distribution is generated by contact inhibition of locomotion, a… …   Dictionary of molecular biology

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