cold agglutinins
Antibodies that agglutinate particles with greater activity below 32°C. They are IgM antibodies specifically reactive with blood groups I and i in humans, and agglutinate red blood cells on cooling, causing Raynaud\'s phenomenon in vivo.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • cold agglutinin syndrome — the presence of circulating cold agglutinins, usually IgM, which are directed against three types of polysaccharide red cell antigens: I antigens, expressed primarily on adult red cells, i antigens, expressed primarily on cells of fetuses and… …   Medical dictionary

  • cold agglutination — agglutination with cold agglutinins (q.v.), occurring more efficiently below 37°C than at 37°C …   Medical dictionary

  • cold agglutinin — n any of several agglutinins sometimes present in the blood (as that of many patients with primary atypical pneumonia) that at low temperatures agglutinate compatible as well as incompatible red blood cells, including the patient s own called… …   Medical dictionary

  • cold agglutinin — noun also cold hemagglutinin : any of certain agglutinins present in some bloods (as those of many patients with primary atypical pneumonia) that at low temperatures agglutinate compatible as well as incompatible erythrocytes, including the… …   Useful english dictionary

  • agglutination — 1. The process by which suspended bacteria, cells, or other particles are caused to adhere and form into clumps; similar to precipitation, but the particles are larger and are in suspension rather than being in solution. For specific a. reactions …   Medical dictionary

  • blood group — Med. any of various classes into which human blood can be divided according to immunological compatibility, based on the presence or absence of specific antigens on red blood cells. Also called blood type. Cf. ABO system, Rh factor. [1915 20] * * …   Universalium

  • Autoagglutination — represents clumping of an individual s red blood cells (RBCs or erythrocytes) by his or her own serum due to the RBCs being coated on their surface by antibodies.Autoagglutination is seen to occur in a type of immune mediated hemolytic anemia… …   Wikipedia

  • autoagglutination — | ̷ ̷(ˌ) ̷ ̷ at auto I+ noun ( s) Etymology: aut + agglutination : agglutination of an individual s red blood cells by cold agglutinins in his own serum usually at lower than body temperature called also cold agglutination …   Useful english dictionary

  • Angioimmunoblastic T-cell lymphoma — Infobox Disease Name = PAGENAME Caption = DiseasesDB = ICD10 = ICD10|C|84|4|c|81 (ILDS C84.460) ICD9 = ICDO = 9705/3 OMIM = MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = D007119 Angioimmunoblastic T cell lymphoma (AILT) is a mature T… …   Wikipedia

  • warm antibodies — Most IgG antibodies react better at 37°C than at lower temperatures, especially against red cell antigens. These are the warm antibodies as contrasted with cold agglutinins, especially IgM, that agglutinate below 28°C …   Dictionary of molecular biology

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