camptothecin
Cytotoxic plant alkaloid originally isolated from Camptotheca acuminata. Anti-cancer drug, inhibits DNA topoisomerase I.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Camptothecin — Systematic (IUPAC) name (S) 4 ethyl 4 hydroxy 1H pyrano[3 ,4 :6,7]indolizino[1,2 b] quinoline 3,14 (4H,12H) dione Clinical data …   Wikipedia

  • camptothecin — camptothecin. См. камптотецин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Camptothecin — Strukturformel Allgemeines Name Camptothecin Andere Namen …   Deutsch Wikipedia

  • camptothecin — noun An alkaloid, derived from the tree Camptothecin acuminate, that inhibits DNA topomerase and is used as an anticancer drug …   Wiktionary

  • camptothecin — Plant alkaloids consisting of a pentacyclic structure with a lactone ring; inhibitors of topoisomerase I, i.e., topotecan and irinotecan (CPT 11). [Camptotheca, genus name of botanic source] * * * camp·to·the·cin .kamp tə thē sən n an alkaloid… …   Medical dictionary

  • camptothecin — camp·to·the·cin …   English syllables

  • camptothecin — An anticancer drug that belongs to the family of drugs called topoisomerase inhibitors …   English dictionary of cancer terms

  • camptothecin — ˌkamptəˈthēsə̇n noun ( s) Etymology: New Latin Camptotheca, genus name (from campto + theca) + English in : an alkaloid C20H16N2O4 from the wood of a Chinese tree (Camptotheca acuminata) of the family Nyssaceae that has shown some antileukemic… …   Useful english dictionary

  • camptothecin analog — An anticancer drug related in structure to camptothecin, a topoisomerase inhibitor. One such drug is aminocamptothecin …   English dictionary of cancer terms

  • polyglutamate camptothecin — A form of the anticancer drug camptothecin that may have fewer side effects and work better than camptothecin. It is being studied in the treatment of cancer. It is a type of DNA topoisomerase inhibitor. Also called CT 2106 …   English dictionary of cancer terms

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