hypermutation
A rapid production of multiple mutations in a gene or genes through the activation of special mutator genes. The process may be deliberately used to maximize the possibility of creating desirable mutants.

Microbiology. . 2009.

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  • hypermutation — noun a) Frequent mutation b) The organism or gene that results from such a mutation …   Wiktionary

  • hypermutation — hy·per·mu·ta·tion (hi″pər mu taґshən) occurrence of mutations at a higher than normal frequency …   Medical dictionary

  • hypermutation — …   Useful english dictionary

  • Hypermutation somatique — L hypermutation somatique est un phénomène retrouvé dans la génération de la diversité des immunoglobulines produites par les lymphocytes B. Contrairement à la recombinaison somatique (ou recombinaison VDJ) qui a lieu dans la moelle, le processus …   Wikipédia en Français

  • Somatic hypermutation — (or SHM) is a mechanism inside cells that is part of the way the immune system adapts to the new foreign elements which confront it (for example, microbes). SHM diversifies the receptors that the immune system uses to recognize foreign elements… …   Wikipedia

  • Somatische Hypermutation — Als somatische Hypermutation wird das Einfügen von Mutationen in die Antikörpergene einer reifenden B Zelle bezeichnet. Es handelt sich um einen wichtigen Schritt des adaptiven Immunsystems. Mit Hilfe des Enzyms Activation Induced Cytidine… …   Deutsch Wikipedia

  • somatic hypermutation — extremely high frequency point mutations that occur in the genes coding immunoglobulin heavy and light chain V regions during B lymphocyte maturation, leading to the increased affinity of antibodies for antigen seen in the secondary immune… …   Medical dictionary

  • somatic hypermutation — The high frequency of mutation that occurs in the gene segments encoding the variable regions of immunoglobulins during the differentiation of B lymphocytes into antibody producing plasma cells …   Glossary of Biotechnology

  • Antibody — Immunoglobulin redirects here. For the immunoglobulin family, see Immunoglobulin superfamily. Antibodies redirects here. For the film, see Antibodies (film). Each antibody binds to a specific antigen; an interaction similar to a lock and key. An… …   Wikipedia

  • Hipermutación — Saltar a navegación, búsqueda Hypermutation somáticas (o SHM) es un mecanismo dentro de las células que es parte de la forma en que el sistema inmune se adapta a los nuevos elementos extranjeros que se enfrentan (por ejemplo, microbios). SHM… …   Wikipedia Español

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