whole-genome shotgun sequencing
An approach to genome sequencing in which the complete genome is broken into random fragments, which are then individually sequenced. Finally the fragments are placed in the proper order using sophisticated computer programs.

Microbiology. . 2009.

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  • Shotgun Sequencing — bzw. Schrotschusssequenzierung ist in der Molekularbiologie eine Methode zur Sequenzierung langer DNA Stränge. Sie wurde von Frederick Sanger 1982 entwickelt. Hierbei wird die DNA mehrfach kopiert und die Kopien werden zufällig in zahlreiche… …   Deutsch Wikipedia

  • Shotgun sequencing — In genetics, shotgun sequencing, also known as shotgun cloning, is a method used for sequencing long DNA strands. It is named by analogy with the rapidly expanding, quasi random firing pattern of a shotgun.Since the chain termination method of… …   Wikipedia

  • Shotgun sequencing — An approach used to decode a genome by shredding ( shotgunning ) it into smaller fragments of DNA which can then be individually sequenced. The sequences of these fragments are then ordered, based on overlaps in the genetic code, and finally… …   Medical dictionary

  • shotgun genome sequencing — A strategy for sequencing a whole genome, in which the genomic DNA is initially fragmented into pieces small enough to be sequenced. Specialized computer software is then used to piece together the individual sequences to create long contiguous… …   Glossary of Biotechnology

  • Human Genome Project — The Human Genome Project (HGP) was an international scientific research project with a primary goal to determine the sequence of chemical base pairs which make up DNA and to identify the approximately 25,000 genes of the human genome from both a… …   Wikipedia

  • DNA sequencing — Part of a series on Genetics Key components Chromosome DNA • RNA Genome Heredity Mutation Nucleotide Variation …   Wikipedia

  • Full genome sequencing — Genome sequencing redirects here. For the sequencing only of DNA, see DNA sequencing. An image of the 46 chromosomes, making up the diploid genome of human male. (The mitochondrial chromosome is not shown.) Full genome sequencing (FGS), also… …   Wikipedia

  • DNA sequencing theory — is the broad body of work that attempts to lay analytical foundations for DNA sequencing. The practical aspects revolve around designing and optimizing sequencing projects (known as strategic genomics ), predicting project performance,… …   Wikipedia

  • Séquençage par shotgun — Séquençage de l ADN Résultat du séquençage par la méthode de Sanger. L ordre de chaque bande indique la position d un nucléotide A,T,C ou G Le séquençage de l ADN consiste à déterminer l ordre d enchaînement des nucléotides d’un fragment d’ADN… …   Wikipédia en Français

  • Human Genome Sequencing Center — The Baylor College of Medicine Human Genome Sequencing Center (BCM HGSC) was established by Richard A. Gibbs in 1996 when BCM was chosen as one of six worldwide sites to complete the final phase of the International Human Genome Project. Gibbs is …   Wikipedia

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