superantigen
Superantigens are bacterial proteins that stimulate the immune system much more extensively than do normal antigens. They stimulate T-cells to proliferate nonspecifically through simultaneous interaction with class II MHC proteins on antigen-presenting cells and variable regions on the b chain of the T-cell receptor complex. Examples include streptococcal scarlet fever toxins, staphylococcal toxic shock syndrome toxin-1, and streptococcal M protein.

Microbiology. . 2009.

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  • superantigen — noun An antigen, which has a powerful interaction with T lymphocytes …   Wiktionary

  • superantigen — An antigen that interacts with the T cell receptor in a domain outside the antigen recognition site. This interaction induces the activation of larger numbers of T cells than are induced by antigens that are presented in the antigen recognition… …   Medical dictionary

  • superantigen — su·per·antigen …   English syllables

  • superantigen — /supəˈræntidʒən/ (say soohpuh ranteejuhn) noun any of various powerful antigens which initiate a surge of T cells resulting in acute disease such as toxic shock syndrome, or a chronic inflammation as experienced in rheumatic fever …   Australian English dictionary

  • superantigen — ˌ noun Etymology: super + antigen : a substance (as an enterotoxin) that acts as an antigen capable of stimulating much larger numbers of T cells than an ordinary antigen …   Useful english dictionary

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