An objective change in a diseased body that can be directly observed (e.g., a fever or rash).

Microbiology. . 2009.


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  • sign — [sīn] n. [ME signe < OFr < L signum, a mark, token, prob. < base of secare, to cut (see SAW1): orig. sense prob. “incised mark”] 1. something that indicates a fact, quality, etc.; indication; token [black as a sign of mourning] 2. a) a… …   English World dictionary

  • Sign — Sign, n. [F. signe, L. signum; cf. AS. segen, segn, a sign, standard, banner, also fr. L. signum. Cf. {Ensign}, {Resign}, {Seal} a stamp, {Signal}, {Signet}.] That by which anything is made known or represented; that which furnishes evidence; a… …   The Collaborative International Dictionary of English

  • sign — n 1 Sign, mark, token, badge, note, symptom can denote a sensible and usually visible indication by means of which something not outwardly apparent or obvious is made known or revealed. Sign is the most comprehensive of these terms, being… …   New Dictionary of Synonyms

  • Sign — Single par Brown Eyed Girls Face A Sign (Japanese version) Face B Love is… (Jea Miryo) Sortie 26 janvier 2011 …   Wikipédia en Français

  • Sign — Sign, v. t. [imp. & p. p. {Signed}; p. pr. & vb. n. {Signing}.] [OE. seinen to bless, originally, to make the sign of the cross over; in this sense fr. ASS. segnian (from segn, n.), or OF. seignier, F. signer, to mark, to sign (in sense 3), fr. L …   The Collaborative International Dictionary of English

  • sign — vt 1: to affix a signature to: ratify or attest by hand or seal sign a bill into law; specif: to write or mark something (as a signature) on (a document) as an acknowledgment of one s intention to be bound by it 2: to assign or convey formally… …   Law dictionary

  • sign — ► NOUN 1) a thing whose presence or occurrence indicates the probable presence, occurrence, or advent of something else. 2) a signal, gesture, or notice conveying information or an instruction. 3) a symbol or word used to represent something in… …   English terms dictionary

  • sign — [n1] indication, evidence assurance, augury, auspice, badge, beacon, bell, caution, clue, divination, flag, flash, foreboding, foreknowledge, foreshadowing, foretoken, forewarning, gesture, giveaway, handwriting on wall*, harbinger, herald, high… …   New thesaurus

  • Sign — Sign, v. i. 1. To be a sign or omen. [Obs.] Shak. [1913 Webster] 2. To make a sign or signal; to communicate directions or intelligence by signs. [1913 Webster] 3. To write one s name, esp. as a token of assent, responsibility, or obligation.… …   The Collaborative International Dictionary of English

  • sign. — sign. 〈Abk. für lat.〉 signatum * * * sign. = ↑ signatum. * * * sign.,   Abkürzung für signatum. * * * sign. = signatum …   Universal-Lexikon

  • Sign — (Sinj), Marktflecken im Bezirk Verlika des dalmatischen Kreises Spalato, Zoll u. Steueramt, Franciscanerkloster, Obergymnasium, Ruinen eines Bergschlosses, Handel mit der Türkei; 2000 Ew.; dabei Überreste. (Wasserleitung u. Mauerwerk) der… …   Pierer's Universal-Lexikon

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