regulator T-cell


regulator T-cell
Regulator T-cells control the development of effector T-cells. Two types exist: T-helper cells (CD41 cells) and T-suppressor cells. There are three subsets of T-helper cells: TH1, TH2, and TH0. TH1 cells produce IL-2, IFN-g, and TNF-b. They effect cell-mediated immunity and are responsible for delayed-type hypersensitivity reactions and macrophage activation. TH2 cells produce IL-4, IL-5, IL-6, IL-10, IL-13. They are helpers for B-cell antibody responses and humoral immunity; they also support IgE responses and eosinophilia. TH0 cells exhibit an unrestricted cytokine profile.

Microbiology. . 2009.

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