immunoglobulin D
immunoglobulin im`mu*no*glob"ulin ([i^]m`m[-u]*n[-o]*gl[o^]b"[-u]*l[i^]n) n. (1953) any one of a class of globular proteins which are antibodies and are produced by the immune system in animals.

Note: The immunoglobulins form a series of related proteins which are each composed of two pairs of polypeptide chains, called heavy (H) and light (L, meaning of lower molecular weight), all linked together by disulfide bonds. They are subdivided on the basis of the structural and antigenic properties of the H chains into four subgroups, {immunoglobulin G} (IgG), {immunoglobulin A} (IgA), {immunoglobulin M} (IgM), and {immunoglobulin D} (IgD). They are divided also into subclasses. Both H and L chains of anny given class and subclass have regions which are of constant structure within that class, as well as regions which are of variable structure. The variable regions impart the ability to recognize and bind to specific molecular structures, thus providing the organism the capacity to recognize and defend itself against the harmful effects of substances foreign to the body. --Stedman

Syn: Ig. [PJC]


The Collaborative International Dictionary of English. 2000.

Look at other dictionaries:

  • Immunoglobulin D — (IgD) is an antibody isotype that makes up about 1% of proteins in the plasma membranes of immature B lymphocytes where it is usually coexpressed with another cell surface antibody called IgM. IgD is also produced in a secreted form that is found …   Wikipedia

  • immunoglobulin D — n IGD …   Medical dictionary

  • immunoglobulin D — noun one of the five major classes of immunoglobulins; present in blood serum in small amounts • Syn: ↑IgD • Hypernyms: ↑immunoglobulin, ↑Ig, ↑immune serum globulin, ↑immune gamma globulin, ↑immune globulin …   Useful english dictionary

  • immunoglobulin — im mu*no*glob ulin ([i^]m m[ u]*n[ o]*gl[o^]b [ u]*l[i^]n) n. (1953) any one of a class of globular proteins which are antibodies and are produced by the immune system in animals. Note: The immunoglobulins form a series of related proteins which… …   The Collaborative International Dictionary of English

  • immunoglobulin A — immunoglobulin im mu*no*glob ulin ([i^]m m[ u]*n[ o]*gl[o^]b [ u]*l[i^]n) n. (1953) any one of a class of globular proteins which are antibodies and are produced by the immune system in animals. Note: The immunoglobulins form a series of related… …   The Collaborative International Dictionary of English

  • immunoglobulin G — immunoglobulin im mu*no*glob ulin ([i^]m m[ u]*n[ o]*gl[o^]b [ u]*l[i^]n) n. (1953) any one of a class of globular proteins which are antibodies and are produced by the immune system in animals. Note: The immunoglobulins form a series of related… …   The Collaborative International Dictionary of English

  • immunoglobulin M — immunoglobulin im mu*no*glob ulin ([i^]m m[ u]*n[ o]*gl[o^]b [ u]*l[i^]n) n. (1953) any one of a class of globular proteins which are antibodies and are produced by the immune system in animals. Note: The immunoglobulins form a series of related… …   The Collaborative International Dictionary of English

  • Immunoglobulin — A protein produced by plasma cells and lymphocytes. Immunoglobulins are an essential part of the body s immune system which attach to foreign substances, such as bacteria, and assist in destroying them. Abbreviated Ig. The classes of… …   Medical dictionary

  • Immunoglobulin G — (IgG) is a monomeric immunoglobulin, built of two heavy chains γ and two light chains. Each IgG has two antigen binding sites. It is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids,… …   Wikipedia

  • Immunoglobulin class switching — Mechanism of class switch recombination that allows isotype switching in activated B cells Immunoglobulin class switching (or isotype switching or isotypic commutation or class switch recombination(CSR)) is a biological mechanism that changes a B …   Wikipedia

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