DNA ligase
ligase ligase n. (Biochem.) An enzyme which catalyzes creation of a covalent bond between two substrates, resulting in a larger product which is a combination of the two starting materials; especially, {DNA ligase}, an enzyme which creates a phosphate bond between 5' and 3' ends of a DNA chain, resulting in a longer chain of DNA. DNA ligase is important in normal biosynthesis of DNA in the replication cycle of cells. [PJC]

The Collaborative International Dictionary of English. 2000.

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  • DNA ligase — repairing chromosomal damage Identifiers EC number 6.5.1.1 …   Wikipedia

  • DNA-Ligase — Bezeichner Externe IDs CAS Nummer:&# …   Deutsch Wikipedia

  • DNA ligase — DNA li·gase (liґgās) an enzyme of the ligase class that catalyzes the energy driven linkage of a double stranded DNA chain with a free 3′ hydroxyl group to one with a 5′ phosphate group, forming a phosphodiester bond between them …   Medical dictionary

  • DNA-Ligase — DNA Ligase,   Molekulargenetik: Enzym, das DNA Fragmente unter Ausbildung einer Esterbindung zwischen Phosphorsäure und Desoxyribose verknüpft. DNA L. spielt v. a. eine Rolle bei der Reparatur von DNA Schäden (DNA Reparatur) sowie bei der… …   Universal-Lexikon

  • DNA ligase — Enzyme involved in DNA replication. The DNA ligase of E. coliseals nicks in one strand of double stranded DNA, a reaction required for linking precursor fragments during discontinuous synthesis on the lagging strand. Nicks are breaks in the… …   Dictionary of molecular biology

  • DNA ligase — DNR ligazė statusas T sritis chemija apibrėžtis Fermentas, sujungiantis viengrandės DNR fragmentus fosfodiesteriniu ryšiu esant komplementariai DNR matricai. atitikmenys: angl. DNA ligase rus. ДНК лигаза …   Chemijos terminų aiškinamasis žodynas

  • DNA ligase — An enzyme that catalyses a reaction to link two separate DNA molecules via the formation of a phosphodiester bond between the 3 hydroxyl end of one and the 5 phosphate of the other. Its natural role lies in DNA repair and replication. An… …   Glossary of Biotechnology

  • DNA ligase — An enzyme that joins two DNA fragments together through the formation of a new phosphodiester bond …   Dictionary of microbiology

  • DNA ligase —    An enzyme that catalyzes nucleotide phisphodiester bond formation …   Forensic science glossary

  • T4 DNA ligase — An enzyme, present in bacteria infected with bacteriophage T4, which catalyses the joining (ligation) of, and repairs nicks in, duplex DNA molecules. Ligation activity requires that one DNA molecule has a 5 phosphate group, and that the other has …   Glossary of Biotechnology

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