digoxin
digoxin di*gox"in, n. (Chem.) a steroid glycoside, one of the cardiotonic chemical substances which is extracted from the foxglove. It is a white, crystalline substance ({C41H64O14}), and is a 3-substituted triglucoside of a steroid, related structurally to digitalin and digitoxin. It is used as a cardiotonic for treatment of certain heart conditions, such as congestive heart failure. Chemically it is

(3[beta],5[beta],12[beta])-3-[(O-2,6-Dideoxy-[beta]-D-ribo-hexopyranosyl-(1->4)-O-2,6-dideoxy-[beta]-D-ribo-hexopyranosyl-(1->4)-2 , 6-dideoxy-[beta]-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-card-20(22)-enolide. The related compounds {digitalin} and {digoxin} are also extracted from the foxglove ({Digitalis lanata} and {Digitalis purpurea}). The class of steroid glycosides having cardiotonic properties are refered to as the cardiac glycosides. --MI11 [PJC]


The Collaborative International Dictionary of English. 2000.

Look at other dictionaries:

  • digoxin — [dij äks′ən] n. a white, crystalline, purified form of digitalis, C41H64O14, used to improve the heart s pumping action …   English World dictionary

  • Digoxin — Not to be confused with Dioxin. Digoxin Systematic (IUPAC) name 4 [(3S,5R,8R,9S,10S,12R,13S,14S) 3 [(2S,4S,5R,6R) 5 [(2S,4S,5R,6R) 5 [(2S,4S,5R,6R) 4,5 dihydroxy 6 methyl oxan 2 yl]oxy 4 hydroxy 6 methyl oxan 2 yl …   Wikipedia

  • Digoxin — Strukturformel Allgemeines Name Digoxin Summenformel …   Deutsch Wikipedia

  • digoxin — A cardioactive steroid glycoside obtained from Digitalis lanata. Largely eliminated by the kidneys. * * * di·gox·in dij äk sən, dig n a poisonous cardiotonic glycoside C41H64O14 obtained from the leaves of a foxglove (Digitalis lanata) and used… …   Medical dictionary

  • digoxin — n. a cardiac glycoside – a drug extracted from digitalis – that increases the force of heart muscle contraction and decreases heart rate. It is used in the treatment of heart failure and in supraventricular tachycardia (especially to control… …   The new mediacal dictionary

  • digoxin — noun Etymology: International Scientific Vocabulary dig (from New Latin Digitalis) + toxin Date: circa 1930 a poisonous cardiotonic steroid C41H64O14 obtained from a foxglove (Digitalis lanata) and used especially to treat atrial fibrillation …   New Collegiate Dictionary

  • digoxin — /dij ok sin/, n. Pharm. a cardiac glycoside of purified digitalis, C41H64O14, derived from the plant leaves of Digitalis lanata and widely used in the treatment of congestive heart failure. [1930; DIG(ITALIS) + (T)OXIN] * * * …   Universalium

  • digoxin — noun A purified cardiac glycoside extracted from the foxglove plant, Digitalis lanata, widely used in the treatment of heart conditions such as atrial fibrillation. Syn: digitalis …   Wiktionary

  • Digoxin — Di|go|xin [zu ↑ Digitoxin], das; s: ein gegen Herzinsuffizienz eingesetztes ↑ Digitalis Glykosid …   Universal-Lexikon

  • digoxin — [dɪ dʒɒksɪn] noun Chemistry a poisonous compound present in the foxglove and other plants, used to treat irregularities of heart rhythm. Origin 1930s: contr. of digitoxin …   English new terms dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”