Lactam Lac"tam, n. [Lactone + amido.] (Chem.) One of a series of anhydrides of an amido type, analogous to the lactones, as oxindol; a cyclic amide. [1913 Webster]

{beta-lactam} or {[beta]-lactam}, (a) a lactam in which the amide bond is contained within a four-membered ring, which includes the amide nitrogen and the carbonyl carbon. (b) an antibiotic containing a beta-lactam, such as a {penicillin}, {cephalosporin}, or {carbapenem}; also called a {beta-lactam antibiotic}. [informal, laboratory slang] [PJC]

The Collaborative International Dictionary of English. 2000.

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  • Carbapenem — Saltar a navegación, búsqueda Los carbapenems son un tipo de antibiótico betalactámico con amplio espectro de actividad bactericida y son sumamente resistentes a las betalactamasas. Esta clase de antibióticos fueron descubiertos originalmente del …   Wikipedia Español

  • Carbapenem — Carbapenems are a class of beta lactam antibiotics with a broad spectrum of antibacterial activity, and have a structure which renders them highly resistant to beta lactamases. Carbapenem antibiotics were originally developed from thienamycin, a… …   Wikipedia

  • Carbapenem — Carbapeneme, ursprünglich als Thienamycine bezeichnet, sind β Lactam Antibiotika mit breitem Wirkungspektrum. Vertreter sind Imipenem, Ertapenem, Meropenem und Doripenem. Imipenem ist stark nephrotoxisch (nierenschädlich). Zur Nierenprotektion… …   Deutsch Wikipedia

  • carbapenem — noun Any of a class of broad spectrum beta lactam antibiotics that are resistant to enzymatic hydrolysis …   Wiktionary

  • Carbapenem — Car|ba|pe|nem [↑ Carba u. ↑ Penem] bicycl. Grundgerüst einiger synthetischer β Lactam Antibiotika, das sich von dem der Penicilline (↑ Penam) durch den Ersatz des Ringschwefel Atoms durch die Methylengruppe unterscheidet …   Universal-Lexikon

  • carbapenem — /kabəˈpɛnɛm/ (say kahbuh penem) noun a class of broad spectrum antibiotics, used as an antibiotic of last resort for many bacterial infections, such as E. coli. {carb(on) + a + penem} …   Australian English dictionary

  • Doripenem — Systematic (IUPAC) name (4R,5S,6S) 6 (1 hydroxyethyl) 4 methyl 7 oxo 3 [(3S,5S) 5 [(sulfamoylamino)methyl]pyrrolidin 3 yl] sulfanyl 1 azabicyclo[3.2.0]hept 2 ene 2 carboxylic acid …   Wikipedia

  • New Delhi metallo-beta-lactamase 1 — Klebsiella pneumoniae, the bacterium in which NDM 1 was first identified. New Delhi metallo beta lactamase 1 (NDM 1)[1] is an enzyme that makes bacteria resistant to a broad range of beta lactam …   Wikipedia

  • Ertapenem — drugbox IUPAC name = (4 R ,5 S ,6 S ) 3 [(3 S ,5 S ) 5 [(3 carboxyphenyl)carbamoyl] pyrrolidin 3 yl] sulfanyl 6 (1 hydroxyethyl) 4 methyl 7 oxo 1 azabicyclo [3.2.0] hept 2 ene 2 carboxylic acid CAS number = 153832 46 3 ATC prefix = J01 ATC suffix …   Wikipedia

  • Beta-lactamase — Beta lactamases are enzymes (EC number| produced by some bacteria and are responsible for their resistance to beta lactam antibiotics like penicillins, cephalosporins, cephamycins, ertapenems and carbapenems. These antibiotics have a… …   Wikipedia

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