C17H14O4S
rofecoxib ofecoxib (Chem. & Med.) A chemical substance ({C17H14O4S}, molecular weight 314.36) used in medicine as an analgesic to alleviate pain and inflammation; it is a synthetic compound, and is marketed by Merck & Co. under the trade name {Vioxx}, in tablets giving dosages of 12.5 or 25 milligrams. It is classed as a non-steroidal anti-inflammatory drug (NSAID). Chemically, it is 4-[4-(methylsulfony)phenyl]-3-phenyl-2(5H) furanone. Its chemical structure contains two phenyl rings and a furanone ring. It is believed to act by inhibition of prostaglandin biosynthesis, through inhibition of the enzyme cyclooxygenase-2 (COX-2); unlike {aspirin}, it does not inhibit cyclooxygenase-1. [PJC]

The Collaborative International Dictionary of English. 2000.

Look at other dictionaries:

  • C17H14O4S — Rofécoxib Rofécoxib Général No CAS …   Wikipédia en Français

  • Rofecoxib — Systematic (IUPAC) name 4 (4 methylsulfonylphenyl) 3 phenyl 5H furan 2 one Clinical data Pregnancy cat. C ( …   Wikipedia

  • 162011-90-7 — Rofécoxib Rofécoxib Général No CAS …   Wikipédia en Français

  • Rofecoxib — Rofécoxib Rofécoxib Général No CAS …   Wikipédia en Français

  • Rofécoxib — Général Nom IUPAC 4 [4 (méthylsulfonyl)phényl] 3 phénylfuran 2(5H) one No CAS …   Wikipédia en Français

  • Vioxx — Rofécoxib Rofécoxib Général No CAS …   Wikipédia en Français

  • rofecoxib — ofecoxib (Chem. & Med.) A chemical substance ({C17H14O4S}, molecular weight 314.36) used in medicine as an analgesic to alleviate pain and inflammation; it is a synthetic compound, and is marketed by Merck & Co. under the trade name {Vioxx}, in… …   The Collaborative International Dictionary of English

  • Vioxx — rofecoxib ofecoxib (Chem. & Med.) A chemical substance ({C17H14O4S}, molecular weight 314.36) used in medicine as an analgesic to alleviate pain and inflammation; it is a synthetic compound, and is marketed by Merck & Co. under the trade name… …   The Collaborative International Dictionary of English

  • Rofecoxib — Strukturformel Allgemeines Freiname Rofecoxib Andere Namen …   Deutsch Wikipedia

  • Vioxx — Strukturformel Allgemeines Freiname Rofecoxib Ander …   Deutsch Wikipedia

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