ligase ligase n. (Biochem.) An enzyme which catalyzes creation of a covalent bond between two substrates, resulting in a larger product which is a combination of the two starting materials; especially, {DNA ligase}, an enzyme which creates a phosphate bond between 5' and 3' ends of a DNA chain, resulting in a longer chain of DNA. DNA ligase is important in normal biosynthesis of DNA in the replication cycle of cells. [PJC]

The Collaborative International Dictionary of English. 2000.

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  • ligase — [ ligaz ] n. f. • 1981; mot angl.; cf. ligand ♦ Biochim. Enzyme permettant l union de deux molécules avec rupture d une liaison à haut potentiel énergétique. A. D. N. ligase : enzyme catalysant l union de deux fragments d A. D. N. ● ligase nom… …   Encyclopédie Universelle

  • ligase — [lī′gās΄, lī′gāz΄] n. any of a class of enzymes that act as catalysts in chemical reactions in which molecules are linked together, as in the synthesis and repair of DNA or in the formation of recombinant DNA …   English World dictionary

  • Ligase — In biochemistry, a ligase (from the Latin verb ligāre mdash; to bind or to glue together ) is an enzyme that can catalyse the joining of the sugar phosphate backbones of Okazaki fragments of DNA. Generally ligase catalyses the following reaction …   Wikipedia

  • Ligase — En biochimie, une ligase est une enzyme qui catalyse la jonction de deux molécules (en anglais ligation) par de nouvelles liaisons covalentes avec hydrolyse concomitante de l ATP ou d autres molécules similaires. Nomenclature le nom courant des… …   Wikipédia en Français

  • Ligase — Ligasen (v. lat. ligare verbinden , verketten ) sind Enzyme, die das Verknüpfen zweier Moleküle durch eine chemische Bindung katalysieren. Dazu benötigen sie Energie, die aus der Spaltung energiereicher Nukleosidtriphosphate (NTP) stammt. Dabei… …   Deutsch Wikipedia

  • ligase — /luy gays, gayz/, n. Biochem. any of a class of enzymes that catalyze the joining of two molecules by formation of a covalent bond accompanied by the hydrolysis of ATP. [1961; < L lig(are) to tie, bind + ASE] * * * ▪ biochemistry also called… …   Universalium

  • ligase — ligazė statusas T sritis chemija apibrėžtis Fermentas, katalizuojantis kondensacijos (sintezės) reakcijas dalyvaujant didžiaenergiams junginiams. atitikmenys: angl. ligase; synthetase rus. лигаза; синтетаза ryšiai: sinonimas – sintetazė …   Chemijos terminų aiškinamasis žodynas

  • ligase — ligazė statusas T sritis augalininkystė apibrėžtis Fermentas, katalizuojantis sintezės reakcijas, dalyvaujant didžiaenergiams junginiams. atitikmenys: angl. ligase; synthetase rus. лигаза; синтетаза …   Žemės ūkio augalų selekcijos ir sėklininkystės terminų žodynas

  • ligase — See: DNA ligase …   Glossary of Biotechnology

  • ligase — noun Etymology: International Scientific Vocabulary lig (from Latin ligare) + ase Date: 1961 synthetase …   New Collegiate Dictionary

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